Endocrine Abstracts

Blood-borne bacteria, fungi and viral agents can activate cells of the innate immune system by interacting with pattern-recognition or Toll receptors on the surface of immune cells. We demonstrate here that mRNA for Toll receptors is ubiquitously expressed in a range of transformed and normal cell types. These findings raise the possibility that infection could induce an inflammatory response in somatic tissues and this might i), provide a milieu for changes in normal cells th...